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Pattern and Correlates of Hypomagnesemia Among Subset of Diabetes Mellitus

Author(s):

Ihasn Salah Rabea, Karrar Al-Gburi, Ihsan Adnan*, Bilal Hasan, Massa Mohammed and Mariam Mohammed   Pages 1 - 6 ( 6 )

Abstract:


Background: Nowadays, there is an accumulated data about the relation between hypomagnesemia (low Serum Mg level < 0.7 mmol/l) and diabetes.

Objective: In this study, we aimed to determine the prevalence of hypomagnesemia in a carefully diagnosed diabetes patients and to show how some factors could contribute to the prevalence of low serum Mg level among the population under study.

Methods: In short, 62 patients of both type 1 and 2, who attended AL-Sadir medical city/ diabetes and endocrinology centre during the period of the study were included in the study. A detailed history was taken and participants were informed verbally about the procedure of this study. Serum magnesium and creatinine were measured using standardized methods.

Results: The overall prevalence of the hypomagnesemia, among diabetic population involved in this study, was 29.03 % and it was nearly similar in male (29.41 %) and female (28.57 %). The means(SD) of serum Mg level were similar in type 1 and type 2 diabetic patients. Other difference in prevalence among other characteristics has been reported. Within all participants, gender (r = -0.02), fasting blood glucose (r = -0.514) and metformin use (r = -0.014) were negatively correlated with serum Mg level, in contrast to other variables, which were positively correlated. While among type 1 DM, age (r= 0.193), serum creatinine (r= 0.031) and insulin use (r= 0.217) were positively correlated with serum Mg level. In contrast, others were negatively correlated. In type 2 DM, age (r = -0.283) and fasting blood glucose (r = -0.496) were negatively correlated with serum Mg level. On the other hand, other variables were positively correlated with serum Mg level.

Conclusion: Hypomagnesemia prevalence was detected in nearly one-third of the diabetic population, which is quite high prevalence. Some factors have shown to play an essential role in this prevalence. A large study is warranted to address this issue.

Keywords:

Hypomagnesemia, diabetes mellitus, magnesium ion, patients, metformin, serum creatinine, standard deviation

Affiliation:

University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Department of Clinical Pharmacy



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