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Diabetes Mellitus and Renal Function: Current Medical Research and Opinion

Author(s):

Moyad Shahwan*, Nageeb Hassan, Rima Ahd Shaheen, Ahmed Gaili, Ammar Jairoun, Monzer Shahwan, Osama Najjar and Shazia Jamshed   Pages 1 - 11 ( 11 )

Abstract:


Diabetes mellitus (DM) which is defined as high blood glucose level is a major public health worldwide. While discussing DM, the knowledge in this field is unlimited hence a syndrome that populations are living with for more than a decade is always an important matter to keep searching for updates on it. Challenges are always present in different means as comorbidities, poorly controlled DM especially type 2 Diabetes mellitus(T2DM) is considered as a risk factor for a lot of different diseases including but not limited to chronic kidney Disease (CKD). Complications might appear through time, as the aging process changes the body functions, while a significant number of antidiabetic medications are cleared eventually by the kidney; this increase the burden on kidney function placing the diabetic patients at risk. The significant high number of patients with uncontrolled diabetes resulting with kidney disease mirror the importance of this condition on patient’s quality of life. This review presents an overview, pathophysiology, etiology and prevalence of Chronic Kidney Disease (CKD) and abnormal renal parameters correlated with poorly controlled T2DM, with emphasis on and clinical studies involving the association between vitamin D Insufficiency/Deficiency and chronic kidney disease among patients with T2DM.

Keywords:

Diabetes mellitus, chronic kidney disease, type 2 diabetes mellitus, vitamin D deficiency.

Affiliation:

Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman,, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman,, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman,, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman,, Consumer Product Safety Section, Public Health and Safety Department, Dubai Municipality, Dubai,, Diabetes Clinic, AL-Swity Center for Dermatology and Chronic Diseases,, General Directorate of Allied Health Professions, Ministry of Health,, Department of Pharmacy Practice, School of Pharmacy, International Islamic University Malaysia



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